Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDIA5Protein disulfide isomerase family A member 5. (520 aa)    
Predicted Functional Partners:
HSPA5
Heat shock protein family A (Hsp70) member 5.
  
 0.831
ERO1A
Endoplasmic reticulum oxidoreductase 1 alpha.
   
 0.796
ERO1B
Endoplasmic reticulum oxidoreductase 1 beta.
   
 0.796
DNAJC3
DnaJ heat shock protein family (Hsp40) member C3.
  
 0.771
POLR2G
RNA polymerase II subunit G.
    
 
 0.717
ENSCAPP00000001068
annotation not available
  
 0.697
LGMN
Legumain.
    
   0.677
HYOU1
Hypoxia up-regulated 1.
  
 0.663
ENSCAPP00000009408
annotation not available
  
 0.645
RERG
RAS like estrogen regulated growth inhibitor.
    
 0.641
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: medium (58%) [HD]