Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR4Phosphatase and actin regulator 4. (500 aa)    
Predicted Functional Partners:
VAX2
Ventral anterior homeobox 2.
      
 0.743
TMEM252
Transmembrane protein 252.
      
 0.727
CACNA1I
Calcium voltage-gated channel subunit alpha1 I.
      
 0.665
ENSCAPP00000009598
annotation not available
    
 
 0.604
TBL2
Transducin beta like 2.
      
 0.583
CHD7
Chromodomain helicase DNA binding protein 7.
      
 0.579
SSH2
Slingshot protein phosphatase 2.
      
 0.570
TOPORS
TOP1 binding arginine/serine rich protein.
      
 0.569
KIF3A
Kinesin family member 3A.
      
 0.567
ENSCAPP00000000802
annotation not available
    
 
 0.561
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.