Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLR1Toll like receptor 1. (793 aa)    
Predicted Functional Partners:
MYD88
MYD88 innate immune signal transduction adaptor.
   
 0.996
TIRAP
TIR domain containing adaptor protein.
    
 0.955
TOLLIP
Toll interacting protein.
    
 0.936
ENSCAPP00000013134
annotation not available
   
 0.935
TLR2
Toll like receptor 2.
   
 
 0.932
NFKB1
Nuclear factor kappa B subunit 1.
   
 0.919
ENSCAPP00000016386
annotation not available
    
 0.904
ENSCAPP00000015456
annotation not available
    
 0.903
ENSCAPP00000011288
annotation not available
    
 0.889
HSPA4
Heat shock protein family A (Hsp70) member 4.
    
 0.888
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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