STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TYK2Tyrosine kinase 2. (970 aa)    
Predicted Functional Partners:
STAT3
Signal transducer and activator of transcription 3.
   
 0.995
STAT1
Signal transducer and activator of transcription 1.
   
 0.991
IFNLR1
Interferon lambda receptor 1.
    
 0.988
IRF9
Interferon regulatory factor 9.
    
 0.988
PTPN11
Protein tyrosine phosphatase non-receptor type 11.
    
 0.988
STAT4
Signal transducer and activator of transcription 4.
   
 0.987
SOCS3
Suppressor of cytokine signaling 3.
    
 0.984
IL2RB
Interleukin 2 receptor subunit beta.
    
 0.978
STAT6
Signal transducer and activator of transcription 6.
    
 0.978
JAK1
Janus kinase 1.
   
 0.975
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.