MBD3 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MBD3

methyl-CpG binding domain protein 3. (247 aa)

Predicted Functional Partners:

MTA2

0.992

GATAD2A

0.988

GATAD2B

0.985

MTA1

0.985

HDAC2

0.985

ENSCAPP00000005542

0.984

CHD3

0.983

HDAC1

0.983

ENSCAPP00000002180

0.980

ENSCAPP00000015653

0.980

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHD3	ENSCAPP00000002180	ENSCAPP00000014535	ENSCAPP00000002180	Chromodomain helicase DNA binding protein 3.	annotation not available	0.998
CHD3	ENSCAPP00000005542	ENSCAPP00000014535	ENSCAPP00000005542	Chromodomain helicase DNA binding protein 3.	annotation not available	0.998
CHD3	ENSCAPP00000015653	ENSCAPP00000014535	ENSCAPP00000015653	Chromodomain helicase DNA binding protein 3.	annotation not available	0.998
CHD3	GATAD2A	ENSCAPP00000014535	ENSCAPP00000015036	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2A.	0.998
CHD3	GATAD2B	ENSCAPP00000014535	ENSCAPP00000008252	Chromodomain helicase DNA binding protein 3.	GATA zinc finger domain containing 2B.	0.998
CHD3	HDAC1	ENSCAPP00000014535	ENSCAPP00000015327	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 1.	0.999
CHD3	HDAC2	ENSCAPP00000014535	ENSCAPP00000016491	Chromodomain helicase DNA binding protein 3.	Histone deacetylase 2.	0.998
CHD3	MBD3	ENSCAPP00000014535	ENSCAPP00000003500	Chromodomain helicase DNA binding protein 3.	methyl-CpG binding domain protein 3.	0.983
CHD3	MTA1	ENSCAPP00000014535	ENSCAPP00000009643	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1.	0.998
CHD3	MTA2	ENSCAPP00000014535	ENSCAPP00000001927	Chromodomain helicase DNA binding protein 3.	Metastasis associated 1 family member 2.	0.998
ENSCAPP00000002180	CHD3	ENSCAPP00000002180	ENSCAPP00000014535	annotation not available	Chromodomain helicase DNA binding protein 3.	0.998
ENSCAPP00000002180	ENSCAPP00000005542	ENSCAPP00000002180	ENSCAPP00000005542	annotation not available	annotation not available	0.986
ENSCAPP00000002180	ENSCAPP00000015653	ENSCAPP00000002180	ENSCAPP00000015653	annotation not available	annotation not available	0.929
ENSCAPP00000002180	GATAD2A	ENSCAPP00000002180	ENSCAPP00000015036	annotation not available	GATA zinc finger domain containing 2A.	0.991
ENSCAPP00000002180	GATAD2B	ENSCAPP00000002180	ENSCAPP00000008252	annotation not available	GATA zinc finger domain containing 2B.	0.990
ENSCAPP00000002180	HDAC1	ENSCAPP00000002180	ENSCAPP00000015327	annotation not available	Histone deacetylase 1.	0.994
ENSCAPP00000002180	HDAC2	ENSCAPP00000002180	ENSCAPP00000016491	annotation not available	Histone deacetylase 2.	0.993
ENSCAPP00000002180	MBD3	ENSCAPP00000002180	ENSCAPP00000003500	annotation not available	methyl-CpG binding domain protein 3.	0.980
ENSCAPP00000002180	MTA1	ENSCAPP00000002180	ENSCAPP00000009643	annotation not available	Metastasis associated 1.	0.992
ENSCAPP00000002180	MTA2	ENSCAPP00000002180	ENSCAPP00000001927	annotation not available	Metastasis associated 1 family member 2.	0.993