Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DAB1DAB adaptor protein 1. (535 aa)    
Predicted Functional Partners:
LRP8
LDL receptor related protein 8.
    
 0.999
VLDLR
Very low density lipoprotein receptor.
    
 0.997
ENSCAPP00000005376
annotation not available
    
  0.985
LDLR
Low density lipoprotein receptor.
    
 0.979
ENSCAPP00000001307
annotation not available
    
 0.977
APP
Amyloid beta precursor protein.
    
 
 0.963
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.951
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.919
ENSCAPP00000003122
annotation not available
    
  0.917
ENSCAPP00000015345
annotation not available
    
  0.917
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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