Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARCActivity regulated cytoskeleton associated protein. (389 aa)    
Predicted Functional Partners:
DLG4
Discs large MAGUK scaffold protein 4.
   
 
 0.976
APP
Amyloid beta precursor protein.
    
 0.953
PSEN1
Presenilin 1.
    
 
 0.934
CAMK2B
Calcium/calmodulin dependent protein kinase II beta.
    
 
 0.867
PSEN2
Presenilin 2.
    
 
 0.842
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha.
    
 
 0.829
APLP2
Amyloid beta precursor like protein 2.
    
 0.804
RPA1
Replication protein A1.
    
 0.760
GRIN1
Glutamate ionotropic receptor NMDA type subunit 1.
   
 0.739
ENSCAPP00000002126
annotation not available
   
 0.736
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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