close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM1PR/SET domain 1. (813 aa)    
Predicted Functional Partners:
EHMT2
Euchromatic histone lysine methyltransferase 2.
    
 0.822
HDAC2
Histone deacetylase 2.
    
 0.744
EHMT1
Euchromatic histone lysine methyltransferase 1.
    
 0.683
STAT3
Signal transducer and activator of transcription 3.
     
 0.651
IRF4
Interferon regulatory factor 4.
   
 
 0.647
HDAC1
Histone deacetylase 1.
    
 0.638
CIZ1
CDKN1A interacting zinc finger protein 1.
     
 0.595
EZH2
Enhancer of zeste 2 polycomb repressive complex 2 subunit.
    
 0.586
NOX3
NADPH oxidase 3.
   
 0.585
ENSCAPP00000003717
annotation not available
   
 0.583
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.