Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CLEC7AC-type lectin domain containing 7A. (248 aa)    
Predicted Functional Partners:
SYK
Spleen associated tyrosine kinase.
    
 0.993
ENSCAPP00000001061
annotation not available
    
 0.920
CBLB
Cbl proto-oncogene B.
     
  0.917
ENSCAPP00000004047
annotation not available
   
 0.912
TREM2
Triggering receptor expressed on myeloid cells 2.
   
 
 0.890
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 0.869
ENSCAPP00000013530
annotation not available
    
 0.869
ENSCAPP00000013675
annotation not available
     
  0.849
ZAP70
Zeta chain of T cell receptor associated protein kinase 70.
    
 0.832
CARD9
Caspase recruitment domain family member 9.
      
 0.820
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.