Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XRCC4X-ray repair cross complementing 4. (322 aa)    
Predicted Functional Partners:
LIG4
DNA ligase 4.
   
 0.998
XRCC6
X-ray repair cross complementing 6.
    
 0.983
PRKDC
Protein kinase, DNA-activated, catalytic subunit.
     
 0.962
ENSCAPP00000008386
annotation not available
   
 
 0.958
ENSCAPP00000016271
annotation not available
  
 
 0.958
FANCD2
FA complementation group D2.
     
 0.956
ATM
ATM serine/threonine kinase.
     
 0.948
ENSCAPP00000010752
annotation not available
     
  0.947
RCOR1
REST corepressor 1.
     
  0.945
FANCI
FA complementation group I.
     
  0.944
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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