Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENND11DENN domain containing 11. (351 aa)    
Predicted Functional Partners:
MAP3K4
Mitogen-activated protein kinase kinase kinase 4.
    
   0.868
AVL9
AVL9 cell migration associated.
      
 0.760
DENND10
DENN domain containing 10.
      
 0.754
DENND6A
DENN domain containing 6A.
      
 0.752
IGHMBP2
Immunoglobulin mu DNA binding protein 2.
      
 0.580
PNKP
Polynucleotide kinase 3'-phosphatase.
   
  
 0.564
NFXL1
Nuclear transcription factor, X-box binding like 1.
   
  
 0.548
ENSCAPP00000006934
annotation not available
    
   0.532
RIC1
RIC1 homolog, RAB6A GEF complex partner 1.
      
 0.451
FAP
Fibroblast activation protein alpha.
      
 0.447
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.