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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
APBA2Amyloid beta precursor protein binding family A member 2. (750 aa)    
Predicted Functional Partners:
RIMS2
Regulating synaptic membrane exocytosis 2.
   
 
 0.982
APP
Amyloid beta precursor protein.
   
 
 0.969
MPP1
Membrane palmitoylated protein 1.
   
 0.934
STXBP1
Syntaxin binding protein 1.
    
 0.848
STXBP2
Syntaxin binding protein 2.
    
 0.848
MPP2
Membrane palmitoylated protein 2.
    
 0.807
MPP6
Membrane palmitoylated protein 6.
    
 0.807
CAMK2B
Calcium/calmodulin dependent protein kinase II beta.
    
 0.799
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha.
    
 0.799
ENSCAPP00000009598
annotation not available
    
 0.799
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.