SI protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SI

Sucrase-isomaltase. (1550 aa)

Predicted Functional Partners:

ENSCAPP00000000845

0.922

GBA3

0.922

MGAM

0.919

ENSCAPP00000012772

0.919

HKDC1

0.912

HK3

0.912

HK2

0.912

GAA

0.911

ENSCAPP00000002674

0.900

ENSCAPP00000017451

0.900

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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same PNG format, but at higher resolution

... as a vector graphic:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000000845	ENSCAPP00000002674	ENSCAPP00000000845	ENSCAPP00000002674	annotation not available	annotation not available	0.878
ENSCAPP00000000845	ENSCAPP00000012772	ENSCAPP00000000845	ENSCAPP00000012772	annotation not available	annotation not available	0.877
ENSCAPP00000000845	ENSCAPP00000017451	ENSCAPP00000000845	ENSCAPP00000017451	annotation not available	annotation not available	0.878
ENSCAPP00000000845	GAA	ENSCAPP00000000845	ENSCAPP00000004451	annotation not available	Glucosidase alpha, acid.	0.923
ENSCAPP00000000845	GBA3	ENSCAPP00000000845	ENSCAPP00000001432	annotation not available	Glucosylceramidase beta 3 (gene/pseudogene).	0.923
ENSCAPP00000000845	HK2	ENSCAPP00000000845	ENSCAPP00000017289	annotation not available	Hexokinase 2.	0.912
ENSCAPP00000000845	HK3	ENSCAPP00000000845	ENSCAPP00000017203	annotation not available	Hexokinase 3.	0.912
ENSCAPP00000000845	HKDC1	ENSCAPP00000000845	ENSCAPP00000001720	annotation not available	Hexokinase domain containing 1.	0.912
ENSCAPP00000000845	MGAM	ENSCAPP00000000845	ENSCAPP00000000854	annotation not available	Maltase-glucoamylase.	0.872
ENSCAPP00000000845	SI	ENSCAPP00000000845	ENSCAPP00000003640	annotation not available	Sucrase-isomaltase.	0.922
ENSCAPP00000002674	ENSCAPP00000000845	ENSCAPP00000002674	ENSCAPP00000000845	annotation not available	annotation not available	0.878
ENSCAPP00000002674	ENSCAPP00000012772	ENSCAPP00000002674	ENSCAPP00000012772	annotation not available	annotation not available	0.845
ENSCAPP00000002674	GAA	ENSCAPP00000002674	ENSCAPP00000004451	annotation not available	Glucosidase alpha, acid.	0.879
ENSCAPP00000002674	GBA3	ENSCAPP00000002674	ENSCAPP00000001432	annotation not available	Glucosylceramidase beta 3 (gene/pseudogene).	0.466
ENSCAPP00000002674	HK2	ENSCAPP00000002674	ENSCAPP00000017289	annotation not available	Hexokinase 2.	0.492
ENSCAPP00000002674	HK3	ENSCAPP00000002674	ENSCAPP00000017203	annotation not available	Hexokinase 3.	0.492
ENSCAPP00000002674	HKDC1	ENSCAPP00000002674	ENSCAPP00000001720	annotation not available	Hexokinase domain containing 1.	0.492
ENSCAPP00000002674	MGAM	ENSCAPP00000002674	ENSCAPP00000000854	annotation not available	Maltase-glucoamylase.	0.845
ENSCAPP00000002674	SI	ENSCAPP00000002674	ENSCAPP00000003640	annotation not available	Sucrase-isomaltase.	0.900
ENSCAPP00000012772	ENSCAPP00000000845	ENSCAPP00000012772	ENSCAPP00000000845	annotation not available	annotation not available	0.877