Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TIMP3TIMP metallopeptidase inhibitor 3. (202 aa)    
Predicted Functional Partners:
MMP2
Matrix metallopeptidase 2.
   
 0.990
ENSCAPP00000017228
annotation not available
   
 0.979
ADAM17
ADAM metallopeptidase domain 17.
    
 
 0.952
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 
 0.925
MMP3
Matrix metallopeptidase 3.
   
 0.917
MMP12
Matrix metallopeptidase 12.
   
 0.899
MMP13
Matrix metallopeptidase 13.
   
 0.883
MMP10
Matrix metallopeptidase 10.
   
 0.879
MMP15
Matrix metallopeptidase 15.
   
 0.866
ENSCAPP00000001035
annotation not available
   
 0.861
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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