Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FEN1Flap structure-specific endonuclease 1. (380 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
  
 0.999
ENSCAPP00000014899
annotation not available
  
 0.995
WRN
WRN RecQ like helicase.
  
 0.991
POLD1
DNA polymerase delta 1, catalytic subunit.
  
 0.990
APEX1
Apurinic/apyrimidinic endodeoxyribonuclease 1.
  
 0.986
DNA2
DNA replication helicase/nuclease 2.
   
 0.980
POLB
DNA polymerase beta.
   
 0.978
ENSCAPP00000005433
annotation not available
  
 0.977
RAD52
RAD52 homolog, DNA repair protein.
    
 0.977
MSH6
mutS homolog 6.
   
 0.975
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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