GEM protein (Cavia aperea) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

Experiments

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[Homology]

Score

GEM

GTP binding protein overexpressed in skeletal muscle. (296 aa)

Predicted Functional Partners:

ITSN2

0.919

NOS1AP

0.853

ITSN1

0.851

ENSCAPP00000013032

0.851

DOCK4

0.809

MET

0.793

MST1R

0.793

SHANK3

0.779

SHANK1

0.779

NF1

0.744

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DOCK4	GEM	ENSCAPP00000004976	ENSCAPP00000003699	Dedicator of cytokinesis 4.	GTP binding protein overexpressed in skeletal muscle.	0.809
DOCK4	SHANK1	ENSCAPP00000004976	ENSCAPP00000017603	Dedicator of cytokinesis 4.	SH3 and multiple ankyrin repeat domains 1.	0.526
DOCK4	SHANK3	ENSCAPP00000004976	ENSCAPP00000005922	Dedicator of cytokinesis 4.	SH3 and multiple ankyrin repeat domains 3.	0.526
ENSCAPP00000013032	GEM	ENSCAPP00000013032	ENSCAPP00000003699	annotation not available	GTP binding protein overexpressed in skeletal muscle.	0.851
ENSCAPP00000013032	ITSN1	ENSCAPP00000013032	ENSCAPP00000009838	annotation not available	Intersectin 1.	0.947
ENSCAPP00000013032	ITSN2	ENSCAPP00000013032	ENSCAPP00000009309	annotation not available	Intersectin 2.	0.984
ENSCAPP00000013032	MET	ENSCAPP00000013032	ENSCAPP00000006936	annotation not available	MET proto-oncogene, receptor tyrosine kinase.	0.489
ENSCAPP00000013032	MST1R	ENSCAPP00000013032	ENSCAPP00000010541	annotation not available	Macrophage stimulating 1 receptor.	0.489
GEM	DOCK4	ENSCAPP00000003699	ENSCAPP00000004976	GTP binding protein overexpressed in skeletal muscle.	Dedicator of cytokinesis 4.	0.809
GEM	ENSCAPP00000013032	ENSCAPP00000003699	ENSCAPP00000013032	GTP binding protein overexpressed in skeletal muscle.	annotation not available	0.851
GEM	ITSN1	ENSCAPP00000003699	ENSCAPP00000009838	GTP binding protein overexpressed in skeletal muscle.	Intersectin 1.	0.851
GEM	ITSN2	ENSCAPP00000003699	ENSCAPP00000009309	GTP binding protein overexpressed in skeletal muscle.	Intersectin 2.	0.919
GEM	MET	ENSCAPP00000003699	ENSCAPP00000006936	GTP binding protein overexpressed in skeletal muscle.	MET proto-oncogene, receptor tyrosine kinase.	0.793
GEM	MST1R	ENSCAPP00000003699	ENSCAPP00000010541	GTP binding protein overexpressed in skeletal muscle.	Macrophage stimulating 1 receptor.	0.793
GEM	NF1	ENSCAPP00000003699	ENSCAPP00000014562	GTP binding protein overexpressed in skeletal muscle.	Neurofibromin 1.	0.744
GEM	NOS1AP	ENSCAPP00000003699	ENSCAPP00000002398	GTP binding protein overexpressed in skeletal muscle.	Nitric oxide synthase 1 adaptor protein.	0.853
GEM	SHANK1	ENSCAPP00000003699	ENSCAPP00000017603	GTP binding protein overexpressed in skeletal muscle.	SH3 and multiple ankyrin repeat domains 1.	0.779
GEM	SHANK3	ENSCAPP00000003699	ENSCAPP00000005922	GTP binding protein overexpressed in skeletal muscle.	SH3 and multiple ankyrin repeat domains 3.	0.779
ITSN1	ENSCAPP00000013032	ENSCAPP00000009838	ENSCAPP00000013032	Intersectin 1.	annotation not available	0.947
ITSN1	GEM	ENSCAPP00000009838	ENSCAPP00000003699	Intersectin 1.	GTP binding protein overexpressed in skeletal muscle.	0.851