ELOC protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ELOC

Elongin C. (121 aa)

Predicted Functional Partners:

ENSCAPP00000016562

0.997

CUL2

0.995

RBX1

0.995

CUL5

0.995

HIF1A

0.993

ENSCAPP00000005342

0.992

ENSCAPP00000011011

0.992

SOCS2

0.987

ELOA

0.981

ZYG11B

0.970

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Export your current network:

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CUL2	CUL5	ENSCAPP00000003484	ENSCAPP00000012653	Cullin 2.	Cullin 5.	0.798
CUL2	ELOA	ENSCAPP00000003484	ENSCAPP00000001299	Cullin 2.	Elongin A.	0.529
CUL2	ELOC	ENSCAPP00000003484	ENSCAPP00000003711	Cullin 2.	Elongin C.	0.995
CUL2	ENSCAPP00000005342	ENSCAPP00000003484	ENSCAPP00000005342	Cullin 2.	annotation not available	0.975
CUL2	ENSCAPP00000011011	ENSCAPP00000003484	ENSCAPP00000011011	Cullin 2.	annotation not available	0.998
CUL2	ENSCAPP00000016562	ENSCAPP00000003484	ENSCAPP00000016562	Cullin 2.	annotation not available	0.999
CUL2	HIF1A	ENSCAPP00000003484	ENSCAPP00000012359	Cullin 2.	Hypoxia inducible factor 1 subunit alpha.	0.997
CUL2	RBX1	ENSCAPP00000003484	ENSCAPP00000006025	Cullin 2.	Ring-box 1.	0.999
CUL2	SOCS2	ENSCAPP00000003484	ENSCAPP00000013927	Cullin 2.	Suppressor of cytokine signaling 2.	0.543
CUL2	ZYG11B	ENSCAPP00000003484	ENSCAPP00000009132	Cullin 2.	Zyg-11 family member B, cell cycle regulator.	0.997
CUL5	CUL2	ENSCAPP00000012653	ENSCAPP00000003484	Cullin 5.	Cullin 2.	0.798
CUL5	ELOA	ENSCAPP00000012653	ENSCAPP00000001299	Cullin 5.	Elongin A.	0.933
CUL5	ELOC	ENSCAPP00000012653	ENSCAPP00000003711	Cullin 5.	Elongin C.	0.995
CUL5	ENSCAPP00000005342	ENSCAPP00000012653	ENSCAPP00000005342	Cullin 5.	annotation not available	0.998
CUL5	ENSCAPP00000011011	ENSCAPP00000012653	ENSCAPP00000011011	Cullin 5.	annotation not available	0.531
CUL5	ENSCAPP00000016562	ENSCAPP00000012653	ENSCAPP00000016562	Cullin 5.	annotation not available	0.999
CUL5	RBX1	ENSCAPP00000012653	ENSCAPP00000006025	Cullin 5.	Ring-box 1.	0.998
CUL5	SOCS2	ENSCAPP00000012653	ENSCAPP00000013927	Cullin 5.	Suppressor of cytokine signaling 2.	0.997
ELOA	CUL2	ENSCAPP00000001299	ENSCAPP00000003484	Elongin A.	Cullin 2.	0.529
ELOA	CUL5	ENSCAPP00000001299	ENSCAPP00000012653	Elongin A.	Cullin 5.	0.933