Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGF2RInsulin like growth factor 2 receptor. (2172 aa)    
Predicted Functional Partners:
IGF2
Insulin like growth factor 2.
    
 
 0.995
GGA2
Golgi associated, gamma adaptin ear containing, ARF binding protein 2.
    
 
 0.981
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 
 0.979
M6PR
Mannose-6-phosphate receptor, cation dependent.
     
 0.976
GGA3
Golgi associated, gamma adaptin ear containing, ARF binding protein 3.
    
 
 0.975
VPS26A
VPS26, retromer complex component A.
    
 
 0.956
PLIN3
Perilipin 3.
   
 0.950
GAK
Cyclin G associated kinase.
   
 
 0.925
SNX8
Sorting nexin 8.
    
 0.880
TOM1L2
Target of myb1 like 2 membrane trafficking protein.
    
 
 0.852
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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