STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RETRet proto-oncogene. (1067 aa)    
Predicted Functional Partners:
GFRA1
GDNF family receptor alpha 1.
    
 0.990
GFRA2
GDNF family receptor alpha 2.
    
 0.977
DOK1
Docking protein 1.
    
  0.959
NCOA4
Nuclear receptor coactivator 4.
     
 0.957
ARTN
Artemin.
    
 0.944
CCDC6
Coiled-coil domain containing 6.
     
 0.905
SHC1
SHC adaptor protein 1.
    
 0.877
GDNF
Glial cell derived neurotrophic factor.
    
 0.853
GRB2
Growth factor receptor bound protein 2.
    
 0.828
EGFR
Epidermal growth factor receptor.
    
0.825
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.