STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PDE4APhosphodiesterase 4A. (755 aa)    
Predicted Functional Partners:
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
   
 0.951
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
   
 0.951
CAMK2A
Calcium/calmodulin dependent protein kinase II alpha.
   
 0.936
ENSCAPP00000003890
annotation not available
  
 
0.922
AMPD2
Adenosine monophosphate deaminase 2.
     
 0.921
ADK
Adenosine kinase.
     
 0.920
AMPD1
Adenosine monophosphate deaminase 1.
     
 0.918
DCK
Deoxycytidine kinase.
     
 0.915
APRT
Adenine phosphoribosyltransferase.
     
 0.911
ENPP3
Ectonucleotide pyrophosphatase/phosphodiesterase 3.
    
 0.911
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.