Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADAM15ADAM metallopeptidase domain 15. (715 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor bound protein 2.
    
 
 0.957
SNX9
Sorting nexin 9.
    
 
 0.951
SH3PXD2A
SH3 and PX domains 2A.
    
 0.933
SNX33
Sorting nexin 33.
    
 
 0.852
SRC
SRC proto-oncogene, non-receptor tyrosine kinase.
    
 
 0.839
ENSCAPP00000013530
annotation not available
    
 
 0.839
ENSCAPP00000001616
annotation not available
    
 
 0.823
SH3PXD2B
SH3 and PX domains 2B.
    
 0.786
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 
 0.782
FYN
FYN proto-oncogene, Src family tyrosine kinase.
    
   0.763
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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