Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXO42F-box protein 42. (686 aa)    
Predicted Functional Partners:
CUL1
Cullin 1.
    
 
 0.976
SKP1
S-phase kinase associated protein 1.
    
 
 0.956
RBX1
Ring-box 1.
    
 0.952
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
   0.949
CCDC6
Coiled-coil domain containing 6.
    
 
 0.925
TP53
Tumor protein p53.
    
   0.912
PPP4R1
Protein phosphatase 4 regulatory subunit 1.
   
 0.850
CUL3
Cullin 3.
    
 
 0.838
PPP2CB
Protein phosphatase 2 catalytic subunit beta.
    
  0.822
PPP2CA
Protein phosphatase 2 catalytic subunit alpha.
    
  0.822
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.