Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMP2Matrix metallopeptidase 2. (625 aa)    
Predicted Functional Partners:
TIMP2
TIMP metallopeptidase inhibitor 2.
   
 0.996
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 0.990
MMP14
Matrix metallopeptidase 14.
   
 0.979
ENSCAPP00000017228
annotation not available
   
 0.979
THBS1
Thrombospondin 1.
    
 0.964
ENSCAPP00000001391
annotation not available
     
 0.960
ENSCAPP00000013524
annotation not available
   
 0.955
COL4A1
Collagen type IV alpha 1 chain.
   
 0.947
COL18A1
Collagen type XVIII alpha 1 chain.
    
 0.944
EDN1
Endothelin 1.
     
 0.937
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (24%) [HD]