Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF7Rho guanine nucleotide exchange factor 7. (678 aa)    
Predicted Functional Partners:
GIT1
GIT ArfGAP 1.
   
 0.998
ENSCAPP00000000244
annotation not available
    
 0.997
GIT2
GIT ArfGAP 2.
   
 0.996
PAK2
P21 (RAC1) activated kinase 2.
   
 0.996
ENSCAPP00000009712
annotation not available
    
 0.985
ENSCAPP00000013934
annotation not available
    
 0.985
PXN
Paxillin.
    
 0.983
LPXN
Leupaxin.
    
 0.976
ENSCAPP00000013675
annotation not available
    
 0.974
PAK4
P21 (RAC1) activated kinase 4.
    
 0.969
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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