PDLIM3 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PDLIM3

PDZ and LIM domain 3. (338 aa)

Predicted Functional Partners:

SMTN

0.912

PDLIM4

0.907

EHBP1

0.889

ENSCAPP00000005544

0.881

ENSCAPP00000017093

0.857

PDLIM7

0.851

SMTNL1

0.848

MYO6

0.827

LDB3

0.792

ACTN2

0.783

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTN2	ENSCAPP00000017093	ENSCAPP00000004418	ENSCAPP00000017093	Actinin alpha 2.	annotation not available	0.653
ACTN2	LDB3	ENSCAPP00000004418	ENSCAPP00000014145	Actinin alpha 2.	LIM domain binding 3.	0.634
ACTN2	PDLIM3	ENSCAPP00000004418	ENSCAPP00000003975	Actinin alpha 2.	PDZ and LIM domain 3.	0.783
ACTN2	PDLIM4	ENSCAPP00000004418	ENSCAPP00000006436	Actinin alpha 2.	PDZ and LIM domain 4.	0.516
ACTN2	PDLIM7	ENSCAPP00000004418	ENSCAPP00000014730	Actinin alpha 2.	PDZ and LIM domain 7.	0.634
ACTN2	SMTNL1	ENSCAPP00000004418	ENSCAPP00000013513	Actinin alpha 2.	Smoothelin like 1.	0.418
EHBP1	ENSCAPP00000005544	ENSCAPP00000003846	ENSCAPP00000005544	EH domain binding protein 1.	annotation not available	0.835
EHBP1	ENSCAPP00000017093	ENSCAPP00000003846	ENSCAPP00000017093	EH domain binding protein 1.	annotation not available	0.906
EHBP1	LDB3	ENSCAPP00000003846	ENSCAPP00000014145	EH domain binding protein 1.	LIM domain binding 3.	0.820
EHBP1	MYO6	ENSCAPP00000003846	ENSCAPP00000011345	EH domain binding protein 1.	Myosin VI.	0.652
EHBP1	PDLIM3	ENSCAPP00000003846	ENSCAPP00000003975	EH domain binding protein 1.	PDZ and LIM domain 3.	0.889
EHBP1	PDLIM4	ENSCAPP00000003846	ENSCAPP00000006436	EH domain binding protein 1.	PDZ and LIM domain 4.	0.918
EHBP1	PDLIM7	ENSCAPP00000003846	ENSCAPP00000014730	EH domain binding protein 1.	PDZ and LIM domain 7.	0.898
EHBP1	SMTN	ENSCAPP00000003846	ENSCAPP00000012551	EH domain binding protein 1.	Smoothelin.	0.845
EHBP1	SMTNL1	ENSCAPP00000003846	ENSCAPP00000013513	EH domain binding protein 1.	Smoothelin like 1.	0.825
ENSCAPP00000005544	EHBP1	ENSCAPP00000005544	ENSCAPP00000003846	annotation not available	EH domain binding protein 1.	0.835
ENSCAPP00000005544	ENSCAPP00000017093	ENSCAPP00000005544	ENSCAPP00000017093	annotation not available	annotation not available	0.895
ENSCAPP00000005544	LDB3	ENSCAPP00000005544	ENSCAPP00000014145	annotation not available	LIM domain binding 3.	0.820
ENSCAPP00000005544	MYO6	ENSCAPP00000005544	ENSCAPP00000011345	annotation not available	Myosin VI.	0.594
ENSCAPP00000005544	PDLIM3	ENSCAPP00000005544	ENSCAPP00000003975	annotation not available	PDZ and LIM domain 3.	0.881