SIAH2 protein (Cavia aperea) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

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experimentally determined

co-expression

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gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

SIAH2

Siah E3 ubiquitin protein ligase 2. (193 aa)

Predicted Functional Partners:

CTNNB1

0.978

SIAH1

0.966

ENSCAPP00000000186

0.963

ENSCAPP00000012777

0.963

USP13

0.943

PINK1

0.894

HIPK2

0.892

MFN2

0.868

MFN1

0.868

JUP

0.857

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	ENSCAPP00000000186	ENSCAPP00000013273	ENSCAPP00000000186	Catenin beta 1.	annotation not available	0.984
CTNNB1	ENSCAPP00000012777	ENSCAPP00000013273	ENSCAPP00000012777	Catenin beta 1.	annotation not available	0.984
CTNNB1	JUP	ENSCAPP00000013273	ENSCAPP00000000441	Catenin beta 1.	Junction plakoglobin.	0.999
CTNNB1	SIAH1	ENSCAPP00000013273	ENSCAPP00000010512	Catenin beta 1.	Siah E3 ubiquitin protein ligase 1.	0.997
CTNNB1	SIAH2	ENSCAPP00000013273	ENSCAPP00000003983	Catenin beta 1.	Siah E3 ubiquitin protein ligase 2.	0.978
CTNNB1	USP13	ENSCAPP00000013273	ENSCAPP00000006254	Catenin beta 1.	Ubiquitin specific peptidase 13.	0.788
ENSCAPP00000000186	CTNNB1	ENSCAPP00000000186	ENSCAPP00000013273	annotation not available	Catenin beta 1.	0.984
ENSCAPP00000000186	JUP	ENSCAPP00000000186	ENSCAPP00000000441	annotation not available	Junction plakoglobin.	0.822
ENSCAPP00000000186	SIAH1	ENSCAPP00000000186	ENSCAPP00000010512	annotation not available	Siah E3 ubiquitin protein ligase 1.	0.994
ENSCAPP00000000186	SIAH2	ENSCAPP00000000186	ENSCAPP00000003983	annotation not available	Siah E3 ubiquitin protein ligase 2.	0.963
ENSCAPP00000012777	CTNNB1	ENSCAPP00000012777	ENSCAPP00000013273	annotation not available	Catenin beta 1.	0.984
ENSCAPP00000012777	JUP	ENSCAPP00000012777	ENSCAPP00000000441	annotation not available	Junction plakoglobin.	0.822
ENSCAPP00000012777	SIAH1	ENSCAPP00000012777	ENSCAPP00000010512	annotation not available	Siah E3 ubiquitin protein ligase 1.	0.994
ENSCAPP00000012777	SIAH2	ENSCAPP00000012777	ENSCAPP00000003983	annotation not available	Siah E3 ubiquitin protein ligase 2.	0.963
HIPK2	SIAH1	ENSCAPP00000015828	ENSCAPP00000010512	Homeodomain interacting protein kinase 2.	Siah E3 ubiquitin protein ligase 1.	0.975
HIPK2	SIAH2	ENSCAPP00000015828	ENSCAPP00000003983	Homeodomain interacting protein kinase 2.	Siah E3 ubiquitin protein ligase 2.	0.892
JUP	CTNNB1	ENSCAPP00000000441	ENSCAPP00000013273	Junction plakoglobin.	Catenin beta 1.	0.999
JUP	ENSCAPP00000000186	ENSCAPP00000000441	ENSCAPP00000000186	Junction plakoglobin.	annotation not available	0.822
JUP	ENSCAPP00000012777	ENSCAPP00000000441	ENSCAPP00000012777	Junction plakoglobin.	annotation not available	0.822
JUP	SIAH1	ENSCAPP00000000441	ENSCAPP00000010512	Junction plakoglobin.	Siah E3 ubiquitin protein ligase 1.	0.857