MFN2 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

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[Homology]

Score

MFN2

Mitofusin 2. (757 aa)

Predicted Functional Partners:

MARCHF5

0.998

MFN1

0.997

ENSCAPP00000001899

0.994

ENSCAPP00000012837

0.994

OPA1

0.987

PINK1

0.982

SAMM50

0.966

MUL1

0.962

MAVS

0.961

TOMM70

0.942

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000001899	ENSCAPP00000012837	ENSCAPP00000001899	ENSCAPP00000012837	annotation not available	annotation not available	0.709
ENSCAPP00000001899	MARCHF5	ENSCAPP00000001899	ENSCAPP00000006765	annotation not available	Membrane associated ring-CH-type finger 5.	0.404
ENSCAPP00000001899	MFN1	ENSCAPP00000001899	ENSCAPP00000008720	annotation not available	Mitofusin 1.	0.993
ENSCAPP00000001899	MFN2	ENSCAPP00000001899	ENSCAPP00000003987	annotation not available	Mitofusin 2.	0.994
ENSCAPP00000001899	MUL1	ENSCAPP00000001899	ENSCAPP00000000365	annotation not available	Mitochondrial E3 ubiquitin protein ligase 1.	0.450
ENSCAPP00000001899	OPA1	ENSCAPP00000001899	ENSCAPP00000012506	annotation not available	OPA1 mitochondrial dynamin like GTPase.	0.786
ENSCAPP00000001899	PINK1	ENSCAPP00000001899	ENSCAPP00000003089	annotation not available	PTEN induced kinase 1.	0.996
ENSCAPP00000001899	TOMM70	ENSCAPP00000001899	ENSCAPP00000014910	annotation not available	Translocase of outer mitochondrial membrane 70.	0.990
ENSCAPP00000012837	ENSCAPP00000001899	ENSCAPP00000012837	ENSCAPP00000001899	annotation not available	annotation not available	0.709
ENSCAPP00000012837	MARCHF5	ENSCAPP00000012837	ENSCAPP00000006765	annotation not available	Membrane associated ring-CH-type finger 5.	0.404
ENSCAPP00000012837	MFN1	ENSCAPP00000012837	ENSCAPP00000008720	annotation not available	Mitofusin 1.	0.993
ENSCAPP00000012837	MFN2	ENSCAPP00000012837	ENSCAPP00000003987	annotation not available	Mitofusin 2.	0.994
ENSCAPP00000012837	MUL1	ENSCAPP00000012837	ENSCAPP00000000365	annotation not available	Mitochondrial E3 ubiquitin protein ligase 1.	0.450
ENSCAPP00000012837	OPA1	ENSCAPP00000012837	ENSCAPP00000012506	annotation not available	OPA1 mitochondrial dynamin like GTPase.	0.786
ENSCAPP00000012837	PINK1	ENSCAPP00000012837	ENSCAPP00000003089	annotation not available	PTEN induced kinase 1.	0.996
ENSCAPP00000012837	TOMM70	ENSCAPP00000012837	ENSCAPP00000014910	annotation not available	Translocase of outer mitochondrial membrane 70.	0.990
MARCHF5	ENSCAPP00000001899	ENSCAPP00000006765	ENSCAPP00000001899	Membrane associated ring-CH-type finger 5.	annotation not available	0.404
MARCHF5	ENSCAPP00000012837	ENSCAPP00000006765	ENSCAPP00000012837	Membrane associated ring-CH-type finger 5.	annotation not available	0.404
MARCHF5	MAVS	ENSCAPP00000006765	ENSCAPP00000012629	Membrane associated ring-CH-type finger 5.	Mitochondrial antiviral signaling protein.	0.852
MARCHF5	MFN1	ENSCAPP00000006765	ENSCAPP00000008720	Membrane associated ring-CH-type finger 5.	Mitofusin 1.	0.997