Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDK1Cyclin dependent kinase 1. (172 aa)    
Predicted Functional Partners:
CCNB2
Cyclin B2.
   
 0.999
CDC20
Cell division cycle 20.
   
 0.999
CCNA1
Cyclin A1.
   
 0.999
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.999
CCNA2
Cyclin A2.
   
 0.999
FZR1
Fizzy and cell division cycle 20 related 1.
   
 0.998
TOP2A
DNA topoisomerase II alpha.
   
 
 0.998
CDC25B
Cell division cycle 25B.
   
 0.998
PLK1
Polo like kinase 1.
   
 0.997
CDK2
Cyclin dependent kinase 2.
   
 0.997
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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