close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK1Cyclin dependent kinase 1. (172 aa)    
Predicted Functional Partners:
CCNB2
Cyclin B2.
   
 0.999
CCNA2
Cyclin A2.
   
 0.999
CDC20
Cell division cycle 20.
   
 0.989
PLK1
Polo like kinase 1.
   
 0.984
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.981
MAD2L1
Mitotic arrest deficient 2 like 1.
   
 0.977
CCNA1
Cyclin A1.
   
 0.976
UBE2C
Ubiquitin conjugating enzyme E2 C.
   
 0.972
CDCA8
Cell division cycle associated 8.
   
 
 0.970
CENPF
Centromere protein F.
   
 0.970
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.