close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TRHRThyrotropin releasing hormone receptor. (417 aa)    
Predicted Functional Partners:
GHRL
Ghrelin and obestatin prepropeptide.
   
 0.816
ENSCAPP00000006458
annotation not available
    
  0.779
ENSCAPP00000005162
annotation not available
    
  0.772
GPR139
G protein-coupled receptor 139.
     
0.716
EDN1
Endothelin 1.
    
  0.707
ENSCAPP00000000375
annotation not available
    
  0.705
GNA14
G protein subunit alpha 14.
    
 0.693
GNAQ
G protein subunit alpha q.
    
 0.673
GNA11
G protein subunit alpha 11.
    
 0.673
GNG2
G protein subunit gamma 2.
    
  0.598
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.