Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PTK6Protein tyrosine kinase 6. (451 aa)    
Predicted Functional Partners:
KHDRBS1
KH RNA binding domain containing, signal transduction associated 1.
    
 0.989
BCAR1
BCAR1 scaffold protein, Cas family member.
    
 0.987
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.967
ENSCAPP00000013002
annotation not available
    
 0.956
ENSCAPP00000003816
annotation not available
    
 0.953
ENSCAPP00000013675
annotation not available
    
 0.953
LYN
LYN proto-oncogene, Src family tyrosine kinase.
   
 0.943
SH2D1A
SH2 domain containing 1A.
   
 0.942
EGFR
Epidermal growth factor receptor.
    
 0.942
DOK1
Docking protein 1.
    
 0.941
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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