STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPRY4Sprouty RTK signaling antagonist 4. (299 aa)    
Predicted Functional Partners:
RNASEH2A
Ribonuclease H2 subunit A.
      
 0.949
GRIN3A
Glutamate ionotropic receptor NMDA type subunit 3A.
      
 0.949
ZBTB16
Zinc finger and BTB domain containing 16.
      
 0.949
HTR5A
5-hydroxytryptamine receptor 5A.
      
 0.942
GRB2
Growth factor receptor bound protein 2.
    
 0.929
NIN
Ninein.
      
 0.836
GOLGA7B
Golgin A7 family member B.
    
   0.825
ENSCAPP00000002975
annotation not available
    
   0.823
TMEM184A
Transmembrane protein 184A.
    
 
 0.798
TMEM184B
Transmembrane protein 184B.
    
 
 0.798
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.