Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CREBBPCREB binding protein. (2048 aa)    
Predicted Functional Partners:
EP300
E1A binding protein p300.
   
 0.999
NCOA1
Nuclear receptor coactivator 1.
   
 0.998
CREB1
cAMP responsive element binding protein 1.
    
 0.998
ENSCAPP00000008952
annotation not available
    
 0.998
TP53
Tumor protein p53.
    
 0.998
NCOA2
Nuclear receptor coactivator 2.
   
 0.997
ENSCAPP00000004857
annotation not available
   
 0.997
HIF1A
Hypoxia inducible factor 1 subunit alpha.
    
 0.997
CTNNB1
Catenin beta 1.
    
 0.997
NCOA3
Nuclear receptor coactivator 3.
   
 0.997
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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