Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
POLD2DNA polymerase delta 2, accessory subunit. (498 aa)    
Predicted Functional Partners:
POLD1
DNA polymerase delta 1, catalytic subunit.
   
 0.999
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.998
POLE
DNA polymerase epsilon, catalytic subunit.
   
 0.998
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 0.997
POLE2
DNA polymerase epsilon 2, accessory subunit.
   
 
 0.997
PCNA
Proliferating cell nuclear antigen.
   
 0.996
PRIM2
DNA primase subunit 2.
  
 0.995
ENSCAPP00000011079
annotation not available
   
 0.994
ENSCAPP00000011399
annotation not available
   
 
 0.994
POLE3
DNA polymerase epsilon 3, accessory subunit.
   
 0.985
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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