STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
POLD2DNA polymerase delta 2, accessory subunit. (498 aa)    
Predicted Functional Partners:
POLD1
DNA polymerase delta 1, catalytic subunit.
   
 0.999
MAD2L2
Mitotic arrest deficient 2 like 2.
    
 0.997
REV3L
REV3 like, DNA directed polymerase zeta catalytic subunit.
   
 0.997
PCNA
Proliferating cell nuclear antigen.
   
 0.997
POLE
DNA polymerase epsilon, catalytic subunit.
   
 0.994
WRN
WRN RecQ like helicase.
    
 0.990
FEN1
Flap structure-specific endonuclease 1.
   
 0.977
ENSCAPP00000011079
annotation not available
   
 0.976
PRIM2
DNA primase subunit 2.
  
 
 0.975
POLE2
DNA polymerase epsilon 2, accessory subunit.
   
 
 0.974
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.