Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FIS1Fission, mitochondrial 1. (141 aa)    
Predicted Functional Partners:
DNM1L
Dynamin 1 like.
    
 0.996
TBC1D15
TBC1 domain family member 15.
    
 0.971
TBC1D17
TBC1 domain family member 17.
    
 0.956
CLDN12
Claudin 12.
     
 0.934
DNM1
Dynamin 1.
    
 0.911
CLDN16
Claudin 16.
   
 0.891
TJP1
Tight junction protein 1.
    
 0.890
ENSCAPP00000002126
annotation not available
    
 0.885
MFN2
Mitofusin 2.
    
 0.877
CLDN18
Claudin 18.
    
 0.866
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]