TFEB protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

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Co-occurrence

Co-expression

Experiments

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[Homology]

Score

TFEB

Transcription factor EB. (532 aa)

Predicted Functional Partners:

MTOR

0.985

MITF

0.972

ENSCAPP00000005560

0.969

RRAGC

0.937

PPP3CB

0.934

PPP3CC

0.929

PPP3CA

0.929

RPTOR

0.927

YWHAB

0.923

ENSCAPP00000002787

0.917

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000002787	ENSCAPP00000005560	ENSCAPP00000002787	ENSCAPP00000005560	annotation not available	annotation not available	0.769
ENSCAPP00000002787	MITF	ENSCAPP00000002787	ENSCAPP00000008973	annotation not available	Melanocyte inducing transcription factor.	0.769
ENSCAPP00000002787	PPP3CA	ENSCAPP00000002787	ENSCAPP00000012381	annotation not available	Protein phosphatase 3 catalytic subunit alpha.	0.999
ENSCAPP00000002787	PPP3CB	ENSCAPP00000002787	ENSCAPP00000017540	annotation not available	Protein phosphatase 3 catalytic subunit beta.	0.995
ENSCAPP00000002787	PPP3CC	ENSCAPP00000002787	ENSCAPP00000002606	annotation not available	Protein phosphatase 3 catalytic subunit gamma.	0.998
ENSCAPP00000002787	TFEB	ENSCAPP00000002787	ENSCAPP00000004108	annotation not available	Transcription factor EB.	0.917
ENSCAPP00000002787	YWHAB	ENSCAPP00000002787	ENSCAPP00000005382	annotation not available	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.	0.497
ENSCAPP00000005560	ENSCAPP00000002787	ENSCAPP00000005560	ENSCAPP00000002787	annotation not available	annotation not available	0.769
ENSCAPP00000005560	MITF	ENSCAPP00000005560	ENSCAPP00000008973	annotation not available	Melanocyte inducing transcription factor.	0.982
ENSCAPP00000005560	MTOR	ENSCAPP00000005560	ENSCAPP00000014395	annotation not available	Mechanistic target of rapamycin kinase.	0.837
ENSCAPP00000005560	PPP3CA	ENSCAPP00000005560	ENSCAPP00000012381	annotation not available	Protein phosphatase 3 catalytic subunit alpha.	0.593
ENSCAPP00000005560	PPP3CB	ENSCAPP00000005560	ENSCAPP00000017540	annotation not available	Protein phosphatase 3 catalytic subunit beta.	0.593
ENSCAPP00000005560	PPP3CC	ENSCAPP00000005560	ENSCAPP00000002606	annotation not available	Protein phosphatase 3 catalytic subunit gamma.	0.593
ENSCAPP00000005560	RPTOR	ENSCAPP00000005560	ENSCAPP00000012948	annotation not available	Regulatory associated protein of MTOR complex 1.	0.616
ENSCAPP00000005560	RRAGC	ENSCAPP00000005560	ENSCAPP00000006157	annotation not available	Ras related GTP binding C.	0.547
ENSCAPP00000005560	TFEB	ENSCAPP00000005560	ENSCAPP00000004108	annotation not available	Transcription factor EB.	0.969
ENSCAPP00000005560	YWHAB	ENSCAPP00000005560	ENSCAPP00000005382	annotation not available	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.	0.556
MITF	ENSCAPP00000002787	ENSCAPP00000008973	ENSCAPP00000002787	Melanocyte inducing transcription factor.	annotation not available	0.769
MITF	ENSCAPP00000005560	ENSCAPP00000008973	ENSCAPP00000005560	Melanocyte inducing transcription factor.	annotation not available	0.982
MITF	MTOR	ENSCAPP00000008973	ENSCAPP00000014395	Melanocyte inducing transcription factor.	Mechanistic target of rapamycin kinase.	0.723