close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PKP2Plakophilin 2. (782 aa)    
Predicted Functional Partners:
JUP
Junction plakoglobin.
   
 0.881
DSG2
Desmoglein 2.
   
 0.870
DSC2
Desmocollin 2.
   
 0.864
ENSCAPP00000013192
annotation not available
   
 0.863
PKP3
Plakophilin 3.
   
 
0.833
FMR1
FMRP translational regulator 1.
    
 0.830
PLEC
Plectin.
   
 0.814
DSG1
Desmoglein 1.
   
 0.811
DSG3
Desmoglein 3.
   
 0.780
DSC1
Desmocollin 1.
   
 0.771
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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