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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STK33Serine/threonine kinase 33. (427 aa)    
Predicted Functional Partners:
ENSCAPP00000017763
annotation not available
   
 0.802
ATF4
Activating transcription factor 4.
   
  0.757
CREB1
cAMP responsive element binding protein 1.
    
 0.755
CREB3L4
cAMP responsive element binding protein 3 like 4.
    
  0.712
CREB3L1
cAMP responsive element binding protein 3 like 1.
    
 0.709
CREB3L3
cAMP responsive element binding protein 3 like 3.
    
  0.700
ENSCAPP00000008507
annotation not available
    
  0.700
CREB3L2
cAMP responsive element binding protein 3 like 2.
    
  0.700
ENSCAPP00000004587
annotation not available
     
 0.696
ATF6B
Activating transcription factor 6 beta.
   
 
  0.695
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.