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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNNPinin, desmosome associated protein. (641 aa)    
Predicted Functional Partners:
RNPS1
RNA binding protein with serine rich domain 1.
   
 0.997
SAP18
Sin3A associated protein 18.
    
 0.996
EIF4A3
Eukaryotic translation initiation factor 4A3.
    
 0.983
ACIN1
Apoptotic chromatin condensation inducer 1.
   
 0.970
ENSCAPP00000004582
annotation not available
   
 0.965
CASC3
CASC3 exon junction complex subunit.
    
 0.957
RBM8A
RNA binding motif protein 8A.
    
 0.951
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 
 0.949
UPF1
UPF1 RNA helicase and ATPase.
     
 0.943
ENSCAPP00000008062
annotation not available
    
  0.943
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.