Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (494 aa)    
Predicted Functional Partners:
INSR
Insulin receptor.
    
 0.998
IGF1R
Insulin like growth factor 1 receptor.
    
 0.998
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.985
EGFR
Epidermal growth factor receptor.
   
 0.975
GIGYF1
GRB10 interacting GYF protein 1.
    
 
 0.966
RET
Ret proto-oncogene.
    
  0.959
PIK3CA
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
    
 0.941
ENSCAPP00000017956
annotation not available
    
 
 0.940
MTOR
Mechanistic target of rapamycin kinase.
    
 0.936
ENSCAPP00000011344
annotation not available
    
 
 0.923
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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