STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRB10Growth factor receptor bound protein 10. (494 aa)    
Predicted Functional Partners:
IGF1R
Insulin like growth factor 1 receptor.
    
 0.991
INSR
Insulin receptor.
    
 0.987
ENSCAPP00000011344
annotation not available
    
 
 0.951
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.814
MTOR
Mechanistic target of rapamycin kinase.
     
 0.808
EGFR
Epidermal growth factor receptor.
   
 0.792
ENSCAPP00000017956
annotation not available
    
 
 0.784
GIGYF1
GRB10 interacting GYF protein 1.
    
 
 0.771
RET
Ret proto-oncogene.
    
 0.757
ENSCAPP00000018565
annotation not available
    
 0.732
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.