MYOC protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

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Textmining

[Homology]

Score

MYOC

Myocilin. (490 aa)

Predicted Functional Partners:

MYL2

0.933

WDR36

0.876

MYL10

0.824

ENSCAPP00000015096

0.793

ENSCAPP00000016433

0.758

ASB10

0.687

ENSCAPP00000008155

0.684

ENSCAPP00000010521

0.667

IFT140

0.658

USH2A

0.641

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB10	ENSCAPP00000008155	ENSCAPP00000010638	ENSCAPP00000008155	Ankyrin repeat and SOCS box containing 10.	annotation not available	0.512
ASB10	ENSCAPP00000015096	ENSCAPP00000010638	ENSCAPP00000015096	Ankyrin repeat and SOCS box containing 10.	annotation not available	0.703
ASB10	ENSCAPP00000016433	ENSCAPP00000010638	ENSCAPP00000016433	Ankyrin repeat and SOCS box containing 10.	annotation not available	0.555
ASB10	MYOC	ENSCAPP00000010638	ENSCAPP00000004259	Ankyrin repeat and SOCS box containing 10.	Myocilin.	0.687
ASB10	WDR36	ENSCAPP00000010638	ENSCAPP00000002292	Ankyrin repeat and SOCS box containing 10.	WD repeat domain 36.	0.698
ENSCAPP00000008155	ASB10	ENSCAPP00000008155	ENSCAPP00000010638	annotation not available	Ankyrin repeat and SOCS box containing 10.	0.512
ENSCAPP00000008155	MYOC	ENSCAPP00000008155	ENSCAPP00000004259	annotation not available	Myocilin.	0.684
ENSCAPP00000010521	MYOC	ENSCAPP00000010521	ENSCAPP00000004259	annotation not available	Myocilin.	0.667
ENSCAPP00000015096	ASB10	ENSCAPP00000015096	ENSCAPP00000010638	annotation not available	Ankyrin repeat and SOCS box containing 10.	0.703
ENSCAPP00000015096	ENSCAPP00000016433	ENSCAPP00000015096	ENSCAPP00000016433	annotation not available	annotation not available	0.449
ENSCAPP00000015096	MYOC	ENSCAPP00000015096	ENSCAPP00000004259	annotation not available	Myocilin.	0.793
ENSCAPP00000015096	WDR36	ENSCAPP00000015096	ENSCAPP00000002292	annotation not available	WD repeat domain 36.	0.741
ENSCAPP00000016433	ASB10	ENSCAPP00000016433	ENSCAPP00000010638	annotation not available	Ankyrin repeat and SOCS box containing 10.	0.555
ENSCAPP00000016433	ENSCAPP00000015096	ENSCAPP00000016433	ENSCAPP00000015096	annotation not available	annotation not available	0.449
ENSCAPP00000016433	MYOC	ENSCAPP00000016433	ENSCAPP00000004259	annotation not available	Myocilin.	0.758
ENSCAPP00000016433	WDR36	ENSCAPP00000016433	ENSCAPP00000002292	annotation not available	WD repeat domain 36.	0.608
IFT140	MYOC	ENSCAPP00000012363	ENSCAPP00000004259	Intraflagellar transport 140.	Myocilin.	0.658
IFT140	USH2A	ENSCAPP00000012363	ENSCAPP00000013847	Intraflagellar transport 140.	Usherin.	0.521
MYL10	MYL2	ENSCAPP00000011857	ENSCAPP00000002428	Myosin light chain 10.	Myosin light chain 2.	0.887
MYL10	MYOC	ENSCAPP00000011857	ENSCAPP00000004259	Myosin light chain 10.	Myocilin.	0.824