Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSCAPP00000004291annotation not available (1014 aa)    
Predicted Functional Partners:
PLEKHA2
Pleckstrin homology domain containing A2.
    
 0.936
APC
APC regulator of WNT signaling pathway.
    
  0.920
PLEKHA1
Pleckstrin homology domain containing A1.
     
  0.898
ENSCAPP00000010613
annotation not available
    
   0.894
PDLIM4
PDZ and LIM domain 4.
    
 0.869
TRIP6
Thyroid hormone receptor interactor 6.
    
 
 0.842
GAB1
GRB2 associated binding protein 1.
    
 0.814
ENTR1
Endosome associated trafficking regulator 1.
    
 
 0.814
ENSCAPP00000001081
annotation not available
 
  
 0.804
APC2
APC regulator of WNT signaling pathway 2.
    
  0.799
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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