Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRMD8FERM domain containing 8. (453 aa)    
Predicted Functional Partners:
RHBDF1
Rhomboid 5 homolog 1.
     
 0.960
RHBDF2
Rhomboid 5 homolog 2.
     
 0.937
ITGB1BP1
Integrin subunit beta 1 binding protein 1.
    
 
 0.769
ENSCAPP00000011206
annotation not available
    
  0.764
CCM2
CCM2 scaffold protein.
    
  0.665
ENSCAPP00000017936
annotation not available
    
  0.665
SH3PXD2A
SH3 and PX domains 2A.
      
 0.629
CCDC60
Coiled-coil domain containing 60.
      
 0.607
SEC22B
SEC22 homolog B, vesicle trafficking protein (gene/pseudogene).
      
 0.590
KCNK7
Potassium two pore domain channel subfamily K member 7.
      
 0.578
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.