SNX18 protein (Cavia aperea) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SNX18

Sorting nexin 18. (408 aa)

Predicted Functional Partners:

SNX9

0.978

ENSCAPP00000002610

0.927

PIK3C2B

0.927

SNX33

0.917

PIK3CD

0.917

PIK3CB

0.917

PIK3CA

0.917

PIK3CG

0.917

GRB2

0.883

ENSCAPP00000013876

0.871

Your Current Organism:

Cavia aperea

NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSCAPP00000002610	ENSCAPP00000013876	ENSCAPP00000002610	ENSCAPP00000013876	annotation not available	annotation not available	0.419
ENSCAPP00000002610	GRB2	ENSCAPP00000002610	ENSCAPP00000011245	annotation not available	Growth factor receptor bound protein 2.	0.903
ENSCAPP00000002610	PIK3C2B	ENSCAPP00000002610	ENSCAPP00000016778	annotation not available	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta.	0.954
ENSCAPP00000002610	PIK3CA	ENSCAPP00000002610	ENSCAPP00000010531	annotation not available	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.	0.950
ENSCAPP00000002610	PIK3CB	ENSCAPP00000002610	ENSCAPP00000008665	annotation not available	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.	0.950
ENSCAPP00000002610	PIK3CD	ENSCAPP00000002610	ENSCAPP00000001323	annotation not available	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.	0.951
ENSCAPP00000002610	PIK3CG	ENSCAPP00000002610	ENSCAPP00000013874	annotation not available	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma.	0.950
ENSCAPP00000002610	SNX18	ENSCAPP00000002610	ENSCAPP00000004314	annotation not available	Sorting nexin 18.	0.927
ENSCAPP00000002610	SNX33	ENSCAPP00000002610	ENSCAPP00000000374	annotation not available	Sorting nexin 33.	0.927
ENSCAPP00000002610	SNX9	ENSCAPP00000002610	ENSCAPP00000013178	annotation not available	Sorting nexin 9.	0.927
ENSCAPP00000013876	ENSCAPP00000002610	ENSCAPP00000013876	ENSCAPP00000002610	annotation not available	annotation not available	0.419
ENSCAPP00000013876	GRB2	ENSCAPP00000013876	ENSCAPP00000011245	annotation not available	Growth factor receptor bound protein 2.	0.725
ENSCAPP00000013876	PIK3C2B	ENSCAPP00000013876	ENSCAPP00000016778	annotation not available	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta.	0.419
ENSCAPP00000013876	SNX18	ENSCAPP00000013876	ENSCAPP00000004314	annotation not available	Sorting nexin 18.	0.871
ENSCAPP00000013876	SNX33	ENSCAPP00000013876	ENSCAPP00000000374	annotation not available	Sorting nexin 33.	0.871
ENSCAPP00000013876	SNX9	ENSCAPP00000013876	ENSCAPP00000013178	annotation not available	Sorting nexin 9.	0.973
GRB2	ENSCAPP00000002610	ENSCAPP00000011245	ENSCAPP00000002610	Growth factor receptor bound protein 2.	annotation not available	0.903
GRB2	ENSCAPP00000013876	ENSCAPP00000011245	ENSCAPP00000013876	Growth factor receptor bound protein 2.	annotation not available	0.725
GRB2	PIK3C2B	ENSCAPP00000011245	ENSCAPP00000016778	Growth factor receptor bound protein 2.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta.	0.974
GRB2	PIK3CA	ENSCAPP00000011245	ENSCAPP00000010531	Growth factor receptor bound protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.	0.989