Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SLC8A1Solute carrier family 8 member A1. (959 aa)    
Predicted Functional Partners:
SLC8A2
Solute carrier family 8 member A2.
   
  0.968
SLC24A4
Solute carrier family 24 member 4.
   
 
 0.919
PRKG1
Protein kinase cGMP-dependent 1.
     
 0.912
ENSCAPP00000007529
annotation not available
     
  0.911
SLC8A3
Solute carrier family 8 member A3.
     
  0.911
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
     
 0.861
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
     
 0.861
ATP1A2
ATPase Na+/K+ transporting subunit alpha 2.
    
 
 0.844
ATP1A1
ATPase Na+/K+ transporting subunit alpha 1.
    
 
 0.807
ATP2A2
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2.
   
 
 0.743
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (32%) [HD]