Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRKFyn related Src family tyrosine kinase. (479 aa)    
Predicted Functional Partners:
MIPOL1
Mirror-image polydactyly 1.
   
    0.974
BNIP2
BCL2 interacting protein 2.
    
  0.966
MST1R
Macrophage stimulating 1 receptor.
   
  0.956
ENSCAPP00000016912
annotation not available
    
 0.950
EGFR
Epidermal growth factor receptor.
    
 0.940
CSK
C-terminal Src kinase.
   
 0.905
SRMS
Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites.
   
   0.900
SH2D1A
SH2 domain containing 1A.
   
 0.826
MET
MET proto-oncogene, receptor tyrosine kinase.
   
  0.766
MATK
Megakaryocyte-associated tyrosine kinase.
   
 0.765
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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