Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
STK36Serine/threonine kinase 36. (977 aa)    
Predicted Functional Partners:
SUFU
SUFU negative regulator of hedgehog signaling.
    
 0.996
KIF7
Kinesin family member 7.
   
 0.986
GLI1
GLI family zinc finger 1.
    
 0.986
KIF21B
Kinesin family member 21B.
   
 0.981
GLI3
GLI family zinc finger 3.
    
 0.966
SMO
Smoothened, frizzled class receptor.
    
 0.962
GLI2
GLI family zinc finger 2.
    
 0.926
PRKACA
Protein kinase cAMP-activated catalytic subunit alpha.
    
  0.913
PRKACB
Protein kinase cAMP-activated catalytic subunit beta.
    
  0.913
IHH
Indian hedgehog signaling molecule.
    
 0.884
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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