Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IGSF21Immunoglobin superfamily member 21. (449 aa)    
Predicted Functional Partners:
IGSF9
Immunoglobulin superfamily member 9.
    
 0.808
CLVS1
Clavesin 1.
   
 
 0.783
IGSF9B
Immunoglobulin superfamily member 9B.
    
 0.744
ENSCAPP00000014101
annotation not available
    
 0.704
ADH5
Alcohol dehydrogenase 5 (class III), chi polypeptide.
   
 
 0.687
ADGRL2
Adhesion G protein-coupled receptor L2.
    
 
 0.686
PALMD
Palmdelphin.
    
 
 0.674
ENSCAPP00000002506
annotation not available
   
  0.666
HSP90AA1
Heat shock protein 90 alpha family class A member 1.
   
  0.666
CDK18
Cyclin dependent kinase 18.
    
 0.665
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.