Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TFAP4Transcription factor AP-4. (326 aa)    
Predicted Functional Partners:
BPTF
Bromodomain PHD finger transcription factor.
    
 
 0.959
FBXW11
F-box and WD repeat domain containing 11.
    
   0.951
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase.
    
   0.930
CDKN1A
Cyclin dependent kinase inhibitor 1A.
    
 0.925
CABIN1
Calcineurin binding protein 1.
    
   0.790
UHRF2
Ubiquitin like with PHD and ring finger domains 2.
    
   0.785
SCMH1
Scm polycomb group protein homolog 1.
      
 0.742
PDE9A
Phosphodiesterase 9A.
    
   0.677
SNRNP200
Small nuclear ribonucleoprotein U5 subunit 200.
    
   0.666
ENSCAPP00000000022
annotation not available
    
   0.618
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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