Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
SH3BP4SH3 domain binding protein 4. (964 aa)    
Predicted Functional Partners:
GIPC2
GIPC PDZ domain containing family member 2.
    
 
 0.957
GIPC1
GIPC PDZ domain containing family member 1.
    
   0.940
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 
 0.917
YWHAG
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma.
    
   0.850
YWHAB
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta.
    
   0.835
ENSCAPP00000002126
annotation not available
    
   0.785
TMEM82
Transmembrane protein 82.
      
 0.752
EPS15L1
Epidermal growth factor receptor pathway substrate 15 like 1.
    
 
 0.682
NTAN1
N-terminal asparagine amidase.
      
 0.681
GIPC3
GIPC PDZ domain containing family member 3.
    
   0.663
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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