Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (196 aa)    
Predicted Functional Partners:
RBPJ
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.957
NOTCH1
Notch receptor 1.
    
 0.933
HEYL
Hes related family bHLH transcription factor with YRPW motif like.
     
  0.911
NOTCH4
Notch receptor 4.
   
 0.888
NOTCH3
Notch receptor 3.
    
 0.878
ENSCAPP00000010296
annotation not available
    
 
 0.865
NOTCH2
Notch receptor 2.
    
 0.862
TP53
Tumor protein p53.
    
 
 0.811
FANCL
FA complementation group L.
    
  0.802
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.772
Your Current Organism:
Cavia aperea
NCBI taxonomy Id: 37548
Other names: Brazilian guinea pig, C. aperea
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